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CAS317318-70-0, GW-501516 Factory Source

GW 501516 is an agonist of PPARδ with EC50 value of 1.1 nM. CAS NO. 317318-70-0 Molecular weight 453.498 Density 1.4± 0.1g /cm3 Boiling point 584.5±60.0 °C at 760 mmHg Molecular formula C21H18F3NO3S2 Melting point 134-136°C MSDS Chinese version/American version Flash point 307.3±32.9 °C

Product Description

GW 501516 has been shown to be the most effective and selective PPARα agonist, with EC50 of 1.1 nM against PPARα and 1000 fold selectivity against other human isoforms PPARα and -γ . GW 501516 showed anti-inflammatory effects in cultured proximal tubule (mProx) cells in mice. GW 501516 inhibited palmitic acid and TNF-α-induced increase in MCP-1 mRNA expression in a dose-dependent manner.

 

Physicochemical Property

Product Name GW-501516
CAS NO. 317318-70-0
Meltling Point 134-136°C
Boiling Point 584.5±60.0 °C at 760 mmHg
Flashing Point 307.3±32.9 °C
Molecular Formula C21H18F3NO3S2
Molecular Weight 453.498
Density 1.4±0.1 g/cm3
Refractive Index 1.619
Appearance White powder


Product Picture

CAS317318-70-0, GW-501516 Factory Source

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