AC-262536 is a selective nonsteroidal androgen receptor regulator (SARM) with beneficial anabolic effects. AC-262536 exhibits strong agonist activity on androgen receptors with affinity in the low nanomolar range (1-10 nM). CAS NO.870888-46-3 Molecular weight 278.34800 Molecular formula C18H18N2O
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AC-262536 inhibited dihydroxytestosterone (DHT) -induced LNCaP proliferation in a dose-dependent way. The effect of 100 nM AC-262536 was significant (47.2±12.2%), and the effect of 1μM treatment reached the plateau (50.7±7.6). Therefore, AC-262536 can be used as a functional antagonist of prostatic cells
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